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Read more:- Resolve Outlook Error 0x80040115
Open Outlook in safe mode
Press Windows Key + R to open Run.
Type the following and click OK:
Outlook /safe
If prompted, choose a profile and click OK.
When the Outlook opens, try sending an email.
If the error does not occur in safe mode, you may have a third-party add-in installed that is creating conflict with the program.